We send our thanks to each and every person working, supporting and researching
to save lives during this difficult time. 

Histologics will continue to do our part
and will be available to ship products as needed.
 SpirabrushCX® •  SoftBiopsy®   •  Soft ECC®  •  Soft ECC-S® 
Call us for more pricing options
(Prices effective Feb. 1, 2019)

Welcome to Histologics - Compassionate Colposcopy

Kylon® Hooked-Fabric Biopsy Technology

Histologics LLC is proud to have developed Soft-ECC® endocervical curette, and the SoftBiopsy® exocervical gynecological biopsy device. Both devices employ a multipatented hooked fabric (Kylon®) that simultaneously biopsies with frictional raking/de-bonding of epithelium from stroma, and traps and stores the tissue for transport to the lab.

The Soft-ECC® and SoftBiopsy® were developed with the patient care experience in mind. The Soft-ECC® design is intended to fit into most endocervical canals and yield an abundant biopsy sample. The ECC procedure is usually performed to remove tissue from the endocervical canal for histological analysis during colposcopy or during the diagnostic work-up of abnormal peri-menopausal or menopausal bleeding. Unlike cytobrush sampling which is a cytologic screening modality, Soft-ECC curettage produces diagnostic histological samples. 

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Procedure Demonstration Videos

These videos demonstrate a gentle approach to cervical tissue collection with our minimally invasive devices.
Soft Biopsy® Procedure with Specimen - Video
Soft ECC® Procedure with Specimen - Video


Research Supports Compassionate New Biopsy Approach
For Women's Health In Cervical Cancer Prevention

Anaheim, CA - A new study compares new, safe, single-use disposable biopsy curettes tipped with a medical fabric (Kylon®) with the pre-existing reusable metal sharp curettes.  Dr. Justin Diedrich at UC Riverside School of Medicine and co- investigators Drs. Sumra Rathore and Joel Bentz, leading pathologists from Aurora Diagnostics, Palm Beach, Florida, have published a large study regarding over 10,000 colposcopy work-ups after abnormal Pap Smears and Human Papillomavirus testing in the July e-issue of the Journal of Lower Genital Tract Disease. Dr. Diedrich stated  Our study proved the new brushes are superior in tissue yield with which the colposcopists discovered disease that the older devices missed.

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"I think I speak for all of the providers in our large group & can say these products have been a game changer for our patients. The satisfaction and comfort is amazing and pathology also appreciates the excellent tissue quality. Will never go back to the old very painful methods. Please feel free to send any San Antonio & surrounding area patients our way. Excellent product!"
Henry Garza MD, FACOG
Acacia OBG Schertz - NE San Antonio Chief of Obstetrics & Gynecology Section
Baptist Healthcare System San Antonio, TX
"I’m really pleased with the instruments you developed and am using them exclusively. Nice samples, not much discomfort, not too deep, and nothing to sterilize!"
Myron R. Kanofsky M.D,
Orange, CA OBGYN Colposcopist

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Soft-ECC® and SoftBiopsy® and Kylon®are registered trademarks of Histologics® LLC.

Histologics products are FDA registered and compliant. See Regulatory Compliance.